Artikel
Comparison of treatment choices in rats formed spinal infection related to implant
Suche in Medline nach
Autoren
Veröffentlicht: | 13. Mai 2014 |
---|
Gliederung
Text
Objective: After constitution spinal implant infection in rats we want to compare antibiotic, irrigation and removal of implant if are effective for the Treatment.
Method: Wistar strain 40 albino female rats applied to the lumbar 5 laminectomy laminectomy site titanium implants placed 10 8 CFU / 1 cc of Methicillin-Resistant Staphylococcus aureus (MRSA) strains were inoculated animals into five groups were separated. As a group of eight rats preliminary study evaluated only the first infection was created. One of the other four groups as control group while trying the other groups only antibiotics, antibiotic treatment with antibiotics, irrigation and implants were removed. A week later, the rats were sacrificed and tissue samples were obtained from the microbiological examination was performed.
Results: All the tissue examples studied by calculation number of bacteria as CFU / gr. Results are compared by Kruskal-Wallis variance analysis and Mann-Whitney-test. When we compare the treatments with the control group we found that all the treatments were effective.
Conclusions: When the treatment results are compared with the control group we found that statistically most significant treatment is reoperation to remove the implant (p=0.02). But in comparison of treatments we found no difference in between.