Artikel
Malignant transformation of an intracranial dermoid tumour into a squamous cell carcinoma
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Autoren
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Kay Mursch
- Zentralklinik, Neurochirurgie, Bad Berka, Deutschland
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Ntenis Nerntengian
- Zentralklinik, Neurochirurgie, Bad Berka, Deutschland
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Wolfgang Brück
- Universitätsmedizin Göttingen, Neuropathologie, Göttingen, Deutschland
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Julianne Behnke-Mursch
- Zentralklinik, Neurochirurgie, Bad Berka, Deutschland
| Veröffentlicht: | 18. Juni 2018 |
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Gliederung
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Objective: Dermoid cysts are benign intracranial tumours, butmalignant transformation into a squamous cell carcinomamay rarely occur. We present the special features of a case in which the second relapse of a dermoid was diagnosed as a squamous cell carcinoma.
Methods: A young, with the exception of a congenital trochlear palsy otherwise healthy woman was operated on an intrasylvian dermoid tumour at the age of 27 and on the first relapse at 29.Controls excluded atumourrelapsefor almost 4 years. Then she developed aphasia and memory deficits. Within 6 months a large, contrast-enhancing mass, surrounded by a large oedema, had developed.
Results: Recraniotomy was performed. Intra-operatively, in contrast to the first operations, the surrounded tissue was invaded. The patient recovered well from a lenticulostriatal infarction and subsequently underwent radiation therapy
Conclusion: Most reports aboutan intracranial tumour transforming into a squamous cell carcinoma deal withepidermoid origin, diagnosed atfirst surgery. In this case, we could prove a dermoid tumour, which was benign two times before. These tumours have to be followed closely after resection because of possibility of rapid growth.
